生物酶由于其特有的高催化效率、高特异选择性、温和的反应条件及更少的三废排放等优点，在制药工业中的现实效应不断扩大，尤其在过程替代、实现更绿色的制药工艺中发挥了重要作用，其重要地位获得了广泛认可。本公司针对多种用于制备手性中间体的特种酶进行了研究开发，包括羰基还原酶、醇脱氢酶、转氨酶、脂肪酶、酰化酶、腈水解酶等。综合各大客户所反馈工业数据，相比原化学转化或拆分工艺，在采用生物酶工艺后，反应总收率平均提高10%以上，单位时间产品产率平均提高40%-50%，三废排放降低20%以上。

酶法催化已经在阿托伐他汀、瑞舒伐他汀、度洛西汀、西他列汀等重磅药物的生产中获得了广泛应用。

Due to its unique advantages of high catalytic efficiency, high specificity, mild reaction conditions and less waste emissions, biological enzymes in the pharmaceutical industry, the practical effect of expanding, especially in the process of replacement, to achieve a greener pharmaceutical process has played an important role, its important status has been widely recognized. The company has developed a variety of enzymes for the preparation of chiral intermediates, including carbonyl reductase, alcohol dehydrogenase, transaminase, lipase, acylase, nitrile hydrolase, etc. . According to the industrial data from the customers, the total yield of the reaction is increased by more than 10% , and the product yield per unit time is increased by 40% -50% , reduce the discharge of three wastes by more than 20% . Enzyme catalysis has been widely used in the production of Atorvastatin, rosuvastatin, Duloxetine, sitagliptin and other blockbuster drugs.

酶应用反应举例：